virulence strain k pneumoniae atcc 700603 (ATCC)
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Virulence Strain K Pneumoniae Atcc 700603, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 4202 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Article Title: Emergence and characterization of a novel ST627-KL8 carbapenem-resistant Klebsiella pneumoniae lineage associated with ICU transmission in a tertiary hospital, China
Journal: Frontiers in Microbiology
doi: 10.3389/fmicb.2025.1723336
Figure Legend Snippet: The mucoviscosity (A) , capsule quantification (B) , and serum resistance (C) of ST627-KL8 strains. (A) Mucoviscosity in three ST627-KL8 clinical strains, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603. The mucoviscosity of strains was determined by a semi-quantitative measurement. (B) Capsule uronic acid production in three ST627-KL8 clinical strains, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603. (C) The resistance of strains against human serum. The serum killing assays were performed by incubating three ST627-KL8 isolates, K. pneumoniae ATCC 43816 and K. pneumoniae ATCC 700603, with human serum for 1, 2, or 3 h at 37°C. Data are presented as mean ± SD derived from three separate experiments. One-way ANOVA with Dunnett’s test was used to analyze data, **** p < 0.0001. For panel (C) , **** p < 0.0001 and *** p < 0.001 indicated ST627-KL8 versus K. pneumoniae ATCC 43816, #### p < 0.0001 and ### p < 0.001 for ST627-KL8 versus K. pneumoniae ATCC 700603.
Techniques Used: Derivative Assay
Figure Legend Snippet: Virulence assessment of three ST627-KL8 CRKP isolates in the G. mellonella infection model. Larvae were injected with PBS (negative control), reference strains K. pneumoniae ATCC 700603 (low-virulence control), K. pneumoniae ATCC 43816 (hypervirulent control), and three ST627-KL8 CRKP isolates (ZJG29565, ZJG30140, ZJG30146) separately. Survival was monitored over time ( n = 30 larvae per group). Survival curves were generated using the Kaplan–Meier method, and statistical significance between groups was determined by the Log-rank test. Data are representative of three independent experiments.
Techniques Used: Infection, Injection, Negative Control, Control, Generated
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Derivative Assay:Article Title: Emergence and characterization of a novel ST627-KL8 carbapenem-resistant Klebsiella pneumoniae lineage associated with ICU transmission in a tertiary hospital, China Article Snippet: In the Galleria mellonella model, ST627-KL8 exhibited intermediate virulence (66.7%–76.7% survival), between the Infection:Article Title: Emergence and characterization of a novel ST627-KL8 carbapenem-resistant Klebsiella pneumoniae lineage associated with ICU transmission in a tertiary hospital, China Article Snippet: In the Galleria mellonella model, ST627-KL8 exhibited intermediate virulence (66.7%–76.7% survival), between the Injection:Article Title: Emergence and characterization of a novel ST627-KL8 carbapenem-resistant Klebsiella pneumoniae lineage associated with ICU transmission in a tertiary hospital, China Article Snippet: In the Galleria mellonella model, ST627-KL8 exhibited intermediate virulence (66.7%–76.7% survival), between the Negative Control:Article Title: Emergence and characterization of a novel ST627-KL8 carbapenem-resistant Klebsiella pneumoniae lineage associated with ICU transmission in a tertiary hospital, China Article Snippet: In the Galleria mellonella model, ST627-KL8 exhibited intermediate virulence (66.7%–76.7% survival), between the Control:Article Title: Emergence and characterization of a novel ST627-KL8 carbapenem-resistant Klebsiella pneumoniae lineage associated with ICU transmission in a tertiary hospital, China Article Snippet: In the Galleria mellonella model, ST627-KL8 exhibited intermediate virulence (66.7%–76.7% survival), between the Generated:Article Title: Emergence and characterization of a novel ST627-KL8 carbapenem-resistant Klebsiella pneumoniae lineage associated with ICU transmission in a tertiary hospital, China Article Snippet: In the Galleria mellonella model, ST627-KL8 exhibited intermediate virulence (66.7%–76.7% survival), between the |